Chronic Urticaria Index
Order Name
CU INDEX
Test Number: 5587555
Revision Date 12/12/2022
Test Number: 5587555
Revision Date 12/12/2022
| Test Name | Methodology | LOINC Code |
|---|---|---|
|
Chronic Urticaria Index
|
Ex-Vivo challenge and cell culture/Histamine analysis |
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment |
| Preferred | 1.5 mL (0.15 mL) | Serum | Clot Activator (SST or Red No-Gel) | Room Temperature |
| Instructions | Specimen Type: Red-top tube or gel-barrier tube Specimen Storage: Maintain specimen at room temperature Stability: Room temperature up to 1 week Frozen up to 1 year Specimen Collection: Serum should be separated from cells within two hours of venipuncture. Send serum in a plastic transport tube. Special Instructions: Testing referred to Eurofins Viracor LLC TC 2103 Specimen Stability: Ambient: Not Available, Refrigerated : Not Available, Frozen: Not Available |
|||
| GENERAL INFORMATION | |
|---|---|
| Expected TAT | 6 - 11 days |
| Clinical Use | Patients with a chronic form of urticaria who are positive (> 10) with the CU index® have an autoimmune basis for their disease. A positive result does not indicate which autoantibody (anti-IgE, anti-FceRI or anti-FceRII) is present. Ex-Vivo Challenge and cell culture: Donor blood cells are incubated with patient serum, a negative control and a positive control. Following the ex-vivo challenge, the cells are centrifuged and the supernatant is recovered for assay of histamine released. Histamine Analysis: Using a quantitative enzyme immunoassay, the histamine released into the supernatant is measured and compared to the total histamine in the basophils. This test has not been cleared or approved for diagnostic use by the U.S. Food and Drug Administration. |
| Performing Labcorp Test Code | 820022 |
| Notes | Labcorp Test Code: 820022 |
| CPT Code(s) | 86352 |
| Lab Section | Reference Lab |