Sign In
Labcorp Oklahoma, Inc.
Test Directory


Index:

Islet Cell Antigen 512 Autoantibodies (IA-2 Antibody)

Order Name ISLET AG
Test Number: 3809750
Revision Date 12/12/2022
Test Name Methodology LOINC Code
Islet Cell Antigen 512 Autoantibodies (IA-2 Antibody)
Enzyme-Linked Immunosorbent Assay (ELISA) 56718-0 
SPECIMEN REQUIREMENTS
Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment
Preferred 1 mL (0.5mL) Serum Clot Activator SST Frozen
Alternate 1 1 mL (0.5mL) Serum Clot Activator (Red Top, No-Gel) Frozen
Instructions Notes: 0.5 mL (Note: This volume Does NOT allow for repeat testing.)
Specimen Type: Red-top tube or gel-barrier tube
Specimen Storage: FREEZE
Specimen Collection: Transfer the serum into a LabCorp PP transpak frozen purple tube with screw cap (LabCorp ID 49482). Freeze immediately and maintain FROZEN until tested. To avoid delays in turnaround time when requesting multiple test on frozen specimens, PLEASE SUBMIT SEPARATE FROZEN SPECIMENS FOR EACH TEST REQUESTED.
Special Instructions: Testing is performed at Esoterix Endocrinology Laboratory: ES#500255
Specimen Stability: Ambient: 3 days, Refrigerated : 3 days, Frozen: 107 days
GENERAL INFORMATION
Expected TAT 5 - 10 days  
Clinical Use Type 1 diabetes is characterized by lymphocytic cell infiltrate of the pancreatic islets. Measurement of GAD-65, ICA-512, and Insulin Antibody is a highly sensitive means to assess risk and predict onset of Type I diabetes. There is a correlation between the number of positive antibodies and the antibody titers versus the severity of the autoimmune process.

Cross References: Beta-Cell Autoantibody to IA-2 (IA-2 Antibody), Insulinoma Associated 2 Antibody (IA-2 Antibody), Islet Cell Antigen (ICA) 512 (IA-2 Antibody) 
Performing Labcorp Test Code 141531 
Notes Labcorp Test Code: 141531
CPT Code(s) 86341
Lab Section Reference Lab