Hepatitis C Viral RNA Genotype 1 NS5a Drug Resistance
Order Name
Hep C 1 NS5a DR
Test Number: 6905999
Revision Date 04/10/2017
Test Number: 6905999
Revision Date 04/10/2017
| Test Name | Methodology | LOINC Code |
|---|---|---|
|
Hepatitis C Viral RNA Genotype 1 NS5a Drug Resistance
|
Polymerase Chain Reaction/Sequencing |
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment |
| Preferred | 2 mL (1 mL) | Plasma | EDTA (Lavender Top) | Frozen |
| Instructions | Specimen Type: Ship in plasma preparation tubes (PPT(TM)) or screw-capped polypropylene frozen transport tubes. Specimen Storage: FREEZE Specimen Collection: Collect specimen in two PPT(TM) tubes, gel-barrier tubes, or lavender-top (EDTA) tubes. Do NOT use green-top (heparin) tubes. Centrifuge specimen within six hours of collection, remove serum/plasma, and transfer specimen to polypropylene screw-capped tubes, and FREEZE. Specimens drawn into PPT(TM) tubes need to be centrifuged within six hours and frozen. Ship FROZEN. To avoid delays in turnaround time when requesting multiple tests on frozen samples, PLEASE SUBMIT SEPARATE FROZEN SPECIMENS FOR EACH TEST REQUESTED. Special Instructions: Please indicate the patient's HCV genotype (1a or 1b) on the test request form. SUBMIT A SPARATE FROZEN SPECIMEN FOR EACH TEST ORDERED. |
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| GENERAL INFORMATION | |
|---|---|
| Expected TAT | 10-14 days |
| Clinical Use | For detection of mutations in the NS5a gene associated with resistance to NS5a inhibitors (examples: daclatasvir, ledipasvir, ombitasvir, elbasvir and velpatasvir). Testing for NS5a resistance-associated variants prior to initiation of treatment with elbasvir plus grazoprevir in HCV genotype 1a infected patients is recommended |
| Performing Labcorp Test Code | 550325 |
| Notes | Labcorp Test Code: 550325 |
| CPT Code(s) | 87902, 87900 |
| Lab Section | Reference Lab |