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Labcorp Oklahoma, Inc.
Test Directory


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Neuromyelitis Optica (NMO) Antibody (Aquaporin-4 Receptor)

Order Name NMO AB
Test Number: 3805377
Revision Date 06/30/2023
Test Name Methodology LOINC Code
Neuromyelitis Optica (NMO) Antibody (Aquaporin-4 Receptor)
Enzyme-Linked Immunosorbent Assay (ELISA) 68548-7 
SPECIMEN REQUIREMENTS
Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment
Preferred 1 mL (0.2 mL) Serum Clot Activator SST Refrigerated
Instructions Specimen Type: Red-top tube OR gel-barrier tube
Specimen Storage: Refrigerate
Specimen Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Specimen Stability: Ambient: 24 hours, Refrigerated : 14 days, Frozen: 14 days
GENERAL INFORMATION
Expected TAT 3 - 5 days  
Clinical Use Approximately 75 percent of patients with neuromyelitis optica (NMO) express antibodies to the aquaporin-4 (AQP4) receptor. Diagnosis of NMO requires the presence of longitudinally extensive acute myelitis (lesions extending over 3 or more vertebral segments) and optic neuritis. While absence of antibodies to the AQP4 receptor does not rule out the diagnosis of NMO, presence of this antibody is diagnostic for NMO. 
Performing Labcorp Test Code 004210 
Notes Labcorp Test Code: 004210
CPT Code(s) 86051
Lab Section Reference Lab