ALK-EML4 gene fusion by FISH
					Order Name
					
						ALK FISH 
					
					
Test Number: 9100787
Revision Date 10/01/2022
				
			Test Number: 9100787
Revision Date 10/01/2022
| Test Name | Methodology | LOINC Code | 
|---|---|---|
| 
									
										
											ALK-EML4 gene fusion by FISH
										
									 | 
								
									Fluorescence in Situ Hybridization | 
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment | 
| Preferred | See Below | Tissue | Paraffin Block | Room Temperature | 
| Instructions |  Formalin fixed paraffin embedded tissue. Tissue source and block ID containing tumor are required on the requisition form. Pathology permission is required for any alternate sample types.  | 
							|||
| GENERAL INFORMATION | |
|---|---|
| Testing Schedule | Tuesday, Thursday | 
| Expected TAT | 7 Days | 
| Clinical Use |  Cinicial use: Rearrangements of the ALK (anaplastic large cell lymphoma) gene located at chromosome 2p23 is best detected by FISH analysis. Patients with lung adenocarcinoma carrying the ALK - EML4 gene fusion have been reported to have a good response to certain chemotherapeutic medications. | 
				
| CPT Code(s) | 88377 | 
| Lab Section | Reference Lab |