BCR/ABL Gene Rearrangement Quantitative by PCR
Order Name
BCRABL PCR
Test Number: 9101855
Revision Date 10/01/2022
Test Number: 9101855
Revision Date 10/01/2022
| Test Name | Methodology | LOINC Code |
|---|---|---|
|
BCR/ABL Gene Rearrangement Quantitative by PCR
|
Polymerase Chain Reaction |
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment |
| Preferred | 5 mL (3 mL) | Whole Blood | EDTA (Lavender Top) | Refrigerated |
| Instructions | For Best results: Send specimens for testing ASAP. Specimens not going to be tested immediately should be stored refrigerated, specimens kept at room temperature will degrade faster than those kept refrigerated. Frozen samples will be rejected. CRITICAL: Do not open or share tube! Stability: Ambient 1 day(s), Refrigerated 2 day(s), Frozen: Unacceptable. |
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| GENERAL INFORMATION | |
|---|---|
| Testing Schedule | Monday and Thursday |
| Expected TAT | Within 7 day(s) |
| Clinical Use | The bcr/abl rearrangement is detected in 90 to 95% of CML, some acute lymphocytic leukemia (ALL), and, rarely, in acute myelogenous leukemia (AML). Diagnose chronic myelogenous leukemia (CML) in the presence or absence of Philadelphia chromosome. Determine prognosis & relapse. Also used to identify acute lymphocytic leukemia (ALL) patients who have a Philadelphia chromosome. |
| Notes | The bcr/abl gene rearrangement is observed in CML, ALL, and AML. A negative result indicates fewer than 1 leukemic cell per 10,000 normal cells. This test detects only the bcr/abl translocation. It will not detect other translocations that may appear in the terminal phase of CML. |
| CPT Code(s) | 81206, 81207, G0452-26 (can be a combination or all 3 codes) |
| Lab Section | Reference Lab |