Blastomyces dermatitidis Ab
Order Name
Blasto Ab
Test Number: 5501505
Revision Date 02/19/2024
Test Number: 5501505
Revision Date 02/19/2024
Test Name | Methodology | LOINC Code |
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Blastomyces dermatitidis Ab
|
Enzyme immunoassay (EIA) | 16471-5 |
SPECIMEN REQUIREMENTS | ||||
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Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment |
Preferred | 1 mL (0.5 mL) | Serum | Clot Activator (SST or Red No-Gel) | Room Temperature |
Instructions | Specimen Type: Gel-barrier Tube, Serum from a Gel-barrier Tube, Serum from a Red-top Tube, Serum Transfer Tube Special Instructions: If Blastomyces antibodies are equivocal or positive by EIA then Blastomyces Antibodies, Quantitative, DID will be added at an additional charge. Specimen Stability: Ambient: 14 days, Refrigerated : 14 days, Frozen: 14 days |
GENERAL INFORMATION | |
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Expected TAT | 1 - 3 days |
Clinical Use | Recommended test if serology is used to aid in the diagnosis of blastomycosis. Negative fungal serology does not rule out the possibility of current infection. Diagnosis of Blastomycosis relies on a combination of assays, including culture and molecular testing on appropriate specimens and serologic evaluation for both antibodies to and antigen released from Blastomyces. Although culture remains the gold standard method and is highly specific, the organism can take several days to weeks to grow, and sensitivity is diminished in cases of acute or localized disease. Similarily, molecular testing offers high specificity and a rapid turnaround time, however, sensitivity is imperfect. Detection of an antibody response to Blastomyces offers high specificity, however, results may be falsely negative in acutely infected patients and in immunosuppressed patients. A positive result indicates that IgG and/or IgM antibodies to Blastomyces were detected. The presence of antibodies is presumptive evidence that the patient was or is currently infected with (or was exposed to) Blastomyces. A negative result indicates that antibodies to Blastomyces were not detected. The absence of antibodies is presumptive evidence that the patient was not infected with Blastomyces. However, the specimen may have been obtained before antibodies were detectable or the patient may be immunosuppressed. If infection is suspected, another specimen should be collected 7 to 14 days later and submitted for testing. |
Performing Labcorp Test Code | 165052 |
Notes | Labcorp Test Code: 165052 |
CPT Code(s) | 86612; if reflexed, add 86612 |
Lab Section | Reference Lab |