HPV (Human Papillomavirus), 16/18 Genotype
Order Name
HPV 16/18
Test Number: 1516350
Revision Date 09/13/2018
Test Number: 1516350
Revision Date 09/13/2018
| Test Name | Methodology | LOINC Code |
|---|---|---|
|
HPV (Human Papillomavirus), 16/18 Genotype
|
Signal Amplification, Invader chemistry detection |
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment |
| Preferred | See Below | PAP specimen | SurePath Liquid Pap Container (Pap Prep) | Room Temperature |
| Alternate 1 | See Below | PAP specimen | CytoRich Preservative Vial | Room Temperature |
| Instructions | The SurePath Prep Preservative Vial and Rover Cervical Brush are available upon request. Additional Rover Endocervical brushes are also available. The SurePath Preservative Vial should be labeled with the patient's name. The cervix brush should be inserted into the endocervical canal. Apply gentle pressure until the bristles form against the cervix. Maintaining gentle pressure, hold the stem between the thumb and forefinger and rotate the brush Five times in a clockwise direction. Gently remove the brush from the endocervical canal and disconnect the entire brush head from the stem and place it into the CytoRich preservative vial. Cap and label the vial with the patients name. If the endocervical brush is used, it should also be disconnected and placed into the same CytoRich preservative vial as the cervix brush. The endocervical brush should never be used by itself. The PAP SurePath specimen must be less than 14 days from collection for HPV testing to be added. If older than 14 days, a new specimen will have to be collected for HPV testing. Add on reject criteria: The primary specimen cannot be older than 13 days from collection; If greater than 13 days then specimen will need to be recollected. |
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| GENERAL INFORMATION | |
|---|---|
| Testing Schedule | Wed |
| Expected TAT | 2-5 days |
| Clinical Use | Recent data reports HPV 16 and 18 subtyping as a powerful tool in predicting risk for significant dysplasia, especially in women over the age of 30. This test may be requested as a reflex order in conjunction with the reflex HPV High Risk screening assay; such that it will be performed only in cases that are positive for high risk HPV screening (includes multiple high risk HPV subtypes). Subtyping for HPV 16 and 18, if ordered as a reflex test, will only be performed if indicated. Alternatively, for previous HPV High Risk positive patients, it may be ordered as a stand alone test on the Sure Path specimen with or without an accompanying Pap smear order. |
| CPT Code(s) | 87625 |
| Internal Comments | changed to single 87621 (03-11-13)
(Note: CPT Code Changed to 87621X2 on 11/29/12) OLD cpt codes: 83912, 83891, 83903X2, 83892X4, 83896X10 New CPT code changed 11-29-12 to: 87621X2 |
| Lab Section | Molecular Diagnostic |